hi jcr21.2023 the remapping option will help but there will probably be games where it will still be difficult or impossible to play one handed.
For example, every button can be re-mapped to become any of the other buttons so in your case, your right controller can take on any of the buttons from the left controller but it only has 5 buttons/triggers available, so if a game uses more than 5 buttons, you still need the left controller to handle the 6th button etc.
So it depends on the game, if the game uses 5 (or less) buttons during play, but uses a 6th button for a menu or for recentring the view, for example, then you could assign those non-play buttons to the left controller and just puck up that controller when you need to, between play.
If the game uses two thumbsticks during play, then I don't think button remapping will help. However, remapping can swap the left/right thumbsticks, so any game that uses one stick that the user isn't able to use, the swap will help them for sure.
So yeah, remapping will definitely open up more games for single handed play but not all unfortunately.