cleverusername
11 years agoExplorer
Autism Brain Cell Research Glutamate
http://2045.com/news/32712.html
The receptor under study, known as the mGlu5 receptor, becomes activated when it binds to the neurotransmitter glutamate, which is associated with learning and memory. This leads to chain reactions that convert the glutamate's signal into messages traveling inside the cell. (Weev says he has requested a gluten free diet in Jail, but they won't honor his request? )
The findings, published March 25 in The Journal of Neuroscience, also add a significant new dimension to basic brain cell function. Scientists have long assumed that brain cell receptors are only active on the surface of cells. The new study shows that receptors can be active inside cells, and their effects can be considerably different from the same receptors located on the cell surface.
"The traditional wisdom was that receptors inside the cell were either waiting to go to work on the surface or had just finished working there," said O'Malley. "But when we compared how much of the mGlu5 receptor was on the surface of cells to how much was inside it, we were seeing so much more receptor inside the cell -- at least 50 percent, and in some cases as much as 90 percent -- that we wondered if the interior receptors had separate functions."
In the new study, scientists working with cells in a dish linked mGlu5 receptors inside cells to processes that turn down the volume at which brain cells talk to each other. These volume changes, essential for learning and memory, may become exaggerated in people with autism.
Singal to Noise? Reading the whole article, they seem to view NEUROENHANCED or NEURODIVERSE people as having a "problem" that needs to be moderated with medicine, to adjust the volume knobs of the brain cells. KBK was recently talking about the farce that is healthcare, I wonder I wonder (in best alan watts voice) if they want to stop all the sleepers from awakening, giving us new drugs to make us NEUROTYPICAL, we are one big happy family after all, and need to congeal towards the median yes? I am sure they mean well, and just want to bring RAIN MAN into being better able to function in neurotypical society. However breakthroughs at IBM were achieved because RAIN MAN was kept separate from neurotypical society, not chemicalized back into it.
As to reducing or moderating the VOLUME of the brain cells, PUMP UP THE VOLUME! Is what I say. (LOL!)
The receptor under study, known as the mGlu5 receptor, becomes activated when it binds to the neurotransmitter glutamate, which is associated with learning and memory. This leads to chain reactions that convert the glutamate's signal into messages traveling inside the cell. (Weev says he has requested a gluten free diet in Jail, but they won't honor his request? )
The findings, published March 25 in The Journal of Neuroscience, also add a significant new dimension to basic brain cell function. Scientists have long assumed that brain cell receptors are only active on the surface of cells. The new study shows that receptors can be active inside cells, and their effects can be considerably different from the same receptors located on the cell surface.
"The traditional wisdom was that receptors inside the cell were either waiting to go to work on the surface or had just finished working there," said O'Malley. "But when we compared how much of the mGlu5 receptor was on the surface of cells to how much was inside it, we were seeing so much more receptor inside the cell -- at least 50 percent, and in some cases as much as 90 percent -- that we wondered if the interior receptors had separate functions."
In the new study, scientists working with cells in a dish linked mGlu5 receptors inside cells to processes that turn down the volume at which brain cells talk to each other. These volume changes, essential for learning and memory, may become exaggerated in people with autism.
Singal to Noise? Reading the whole article, they seem to view NEUROENHANCED or NEURODIVERSE people as having a "problem" that needs to be moderated with medicine, to adjust the volume knobs of the brain cells. KBK was recently talking about the farce that is healthcare, I wonder I wonder (in best alan watts voice) if they want to stop all the sleepers from awakening, giving us new drugs to make us NEUROTYPICAL, we are one big happy family after all, and need to congeal towards the median yes? I am sure they mean well, and just want to bring RAIN MAN into being better able to function in neurotypical society. However breakthroughs at IBM were achieved because RAIN MAN was kept separate from neurotypical society, not chemicalized back into it.
As to reducing or moderating the VOLUME of the brain cells, PUMP UP THE VOLUME! Is what I say. (LOL!)


