GPU Profiler Issue

Hi, I am an Oculus Quest Unity developer. I have tried to Debug my Quest application by Unity Rendering Profiler window, However, doing so arouse performance issue: the FPS drops from 72FPS to 20 FPS. May I ask why?
By the way, I have also used SnapDragon profiler for specifically profiler GPU performance of the application, but the images cannot be captured.
Any solutions would be highly appreciated!